New Study Suggests GLP-1 Weight-Loss Injections Could Help Some Children With Obesity

A new review suggests that GLP-1 weight-loss injections may be a safe and effective treatment option for some children aged six and older with obesity when prescribed under medical supervision. Researchers found the medications were associated with weight loss, improved blood pressure and better quality of life.

The findings come from a Canadian systematic review and meta-analysis that examined nine studies involving more than 750 children and adolescents between the ages of six and 18. The researchers said the treatment showed promising results but emphasized the need for continued monitoring and further research on long-term safety.

Review Analyzed Nine Clinical Studies

The study reviewed clinical evidence on GLP-1 receptor agonists, a class of medicines used to support weight management in people with obesity.

According to the analysis, children who received the medications experienced measurable improvements in body weight compared with standard treatment. Researchers also observed benefits in blood pressure and overall quality of life.

Side Effects Require Medical Supervision

The review found that nausea was the most commonly reported side effect and occurred more frequently among children receiving GLP-1 treatment.

Researchers stressed that these medications should only be used under the supervision of qualified healthcare professionals following a thorough medical assessment.

Limited Use Already Approved in the UK

Under existing NHS guidelines, specialist centres in the United Kingdom can prescribe GLP-1 medicines such as Mounjaro and Wegovy to some patients under the age of 18 with severe obesity.

The treatment is generally considered only when obesity has led to serious health complications and other treatment approaches have not been effective.

The researchers concluded that while the findings are encouraging, additional long-term studies are needed to better understand the safety and effectiveness of GLP-1 therapies in children.

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